How is Cathflo administered in PICC?
Inject the 2.2 mL of Sterile Water for Injection, USP, into the Cathflo Activase vial, directing the diluent stream into the powder. Slight foaming is not unusual; let the vial stand undisturbed to allow large bubbles to dissipate. Mix by gently swirling until the contents are completely dissolved.
How do you give alteplase to a PICC line?
Doses of 1 to 2 mg injected into the lumen(s) of central venous catheters or PICC lines, allowed to dwell for 15 minutes to 4 hours, then removed by aspiration, have been reported effective in establishing patency. Instill 2 mg/2 ml into the dysfunctional catheter for 2 hours.
Can you Cathflo a central line?
In COOL-1, Cathflo restored function to 88% (112/127) of central lines after up to 2 doses using a 120-minute dwell time for each in catheters with occlusions present for up to 24 hours.
What medication is used to Declot a PICC line?
Drugs used to treat IV Catheter Clot
| Drug name | Rating | Rx/OTC |
|---|---|---|
| View information about alteplase alteplase | Rate | Rx |
| Generic name: alteplase systemic Brand name: Cathflo Activase Drug class: thrombolytics For consumers: dosage, interactions, side effects For professionals: AHFS DI Monograph |
How do you unclog a PICC line?
Use a saline filled 3 cc syringe to flush the line. Generally, it takes very little force on the plunger. No need for a heparin flush. No need for diluted thrombolytic.
Do you flush after Cathflo?
5. If catheter function has been restored, ASPIRATE 4 to 5 mL of blood in patients ≥10 kg or 3 mL in patients <10 kg to remove Cathflo and residual clot. Then discard aspirate and flush the catheter with 0.9% Sodium Chloride, USP. Any unused solution should be discarded.
What do you use to unclog a PICC line?
What happens if you push Cathflo?
Excessive pressure should be avoided when Cathflo Activase is instilled into the catheter. Such force could cause rupture of the catheter or expulsion of the clot into the circulation.
Can you flush Cathflo?
If catheter function has been restored, ASPIRATE 4 to 5 mL of blood in patients ≥10 kg or 3 mL in patients <10 kg to remove Cathflo and residual clot. Then discard aspirate and flush the catheter with 0.9% Sodium Chloride, USP. Any unused solution should be discarded.
What causes a PICC line to clog?
Malfunction: PICC lines can become clogged by substances delivered through the line. There are medications that can help break up the blockage, but the line will sometimes need to be replaced. Infection: A bacterial infection can develop if the ports or insertion sites are not routinely cleaned and cared for.
Is Cathflo a contraindication?
Contraindications. Cathflo Activase should not be administered to patients with known hypersensitivity to alteplase or any component of the formulation.