What is the pathogenesis of tuberculosis?
The cycle of TB infection begins with dispersion of M. tuberculosis aerosols. A dose of one to 10 bacilli are dispersed throughout the air, making the risk of transmission likely. In the patient’s lung, the bacilli are phagocytized by alveolar macrophage cells, which then invade the underlying epithelium.
What are the 5 stages of TB?
There are 3 stages of TB: exposure, latent, and active disease. A TB skin test or a TB blood test can often diagnose the infection. But other testing is also often needed. Treatment exactly as recommended is needed to cure the disease and prevent its spread to other people.
What is tuberculosis disease PDF?
Tuberculosis (TB) is an airborne infectious disease caused by organisms of the Mycobacterium tuberculosis complex. Although primarily a pulmonary pathogen, M. tuberculosis can cause disease in almost any part of the body.
What is the mechanism of pathogenesis?
Pathogenesis is the process by which an infection leads to disease. Pathogenic mechanisms of viral disease include (1) implantation of virus at the portal of entry, (2) local replication, (3) spread to target organs (disease sites), and (4) spread to sites of shedding of virus into the environment.
What are the 5 different types of pathogens?
A variety of microorganisms can cause disease. Pathogenic organisms are of five main types: viruses, bacteria, fungi, protozoa, and worms. Some common pathogens in each group are listed in the column on the right. Infectious agents can grow in various body compartments, as shown schematically in Fig.
What is pathogenesis PDF?
This process of causing disease is termed as Pathogenesis. Pathogenesis is a multi-factorial process which depends on the immune status of the host, the nature of the species or strain (virulence factors) and the number of organisms in the initial exposure.
What are the types of pathogenesis?
Types of pathogenesis include microbial infection, inflammation, malignancy and tissue breakdown. For example, bacterial pathogenesis is the process by which bacteria cause infectious illness. Most diseases are caused by multiple processes.